Thursday, April 12, 2012

Name: Sameeha
Current Event Posting #3
Topic: Health
Title of Article: Closer to using aspirin for cancer prevention
Author: Madison Park
Publication Name: CNN
Date of Publication: April 10, 2012
Length of Article: 1 page

Recent reports show that we are getting closer to using aspirin as part of clinical guidelines in cancer prevention. In the past, the U.S. Preventive Services Task Force has recommended an aspirin regimen for some patients in order to prevent heart problems and reduce the risk of strokes, however an aspirin regimen hasn't been used for cancer prevention before. Studies show that aspirin can reduce the risk of colorectal cancer and colorectal polyps but it can also increase the risk of gastrointestinal hemorrhage. Aspirin can actually increase bleeding because it decreases the amount of clotting that occurs in the bloodstream and anyone with bleeding problems, like hemophilia, should not take it. Doctors have also warned that aspirins should not be given to children under the age of two because there is a possible link of aspirin to Reye's syndrome. Michael Thun, vice president emeritus of epidemiology and surveillance research for the American Cancer Society, wrote that "daily aspirin at doses of 75 mg and above might lower both overall cancer incidence and overall cancer mortality." In a recent study conducted by Dr. Peter M. Rothwell, researchers saw a 20% decrease in cancer incidence in patients between three to five years of the aspirin regimen and a 30% decrease after five or more years. The researchers also found that the amount of cancer deaths among aspirin users reduced from 664 deaths to 562 deaths. Scientists have discovered that this aspirin treatment is only successful at reducing risk of cancer at low doses of 75-160 mg; anything higher than this is not effective. The mechanism by which the aspirin works to reduce the risk of cancer isn't entirely understood by scientists but they think that aspirin helps the body cut off blood supply to cancer growths, preventing them from spreading.

Because aspirin is capable of preventing heart problems, strokes, and possibly cancer, it has been called a miracle drug and a wonder drug. More than one-third of all adults and four-fifths of people with heart disease have been on the aspirin regimen for many years and this number will grow as more and more evidence is found of aspirin's capability to prevent some cancers. Some people are skeptical that taking aspirin, which isn't as powerful as more popular painkillers like Advil and Tylenol, won't be effective. But, aspirin contains special chemicals that Tylenol and Advil don't have that can guard our bodies against diseases like cancer. Doctors are eagerly waiting for more results about aspirins and their ability to prevent some cancers so that they can recommend taking small doses of aspirin to patients as a daily regimen and greatly lower the number of people who die of cancer each year.


10 comments:

  1. This comment has been removed by the author.

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  2. It is unbelievable that aspirin, a common household drug, has to potential to cure both cancer incidence and cancer mortality (colorectal cancer and colorectal polyps) . It is controversial, however, that aspirin can also increase death in people suffering from hemophilia because it can cause gastrointestinal hemorrhages. In Mr. Rothwell's study the 20% decrease in cancer incidence (2-3 years) and 30% decrease in cancer incidence (5+ years) only work on doses between 75-150 MG, usually much lower than one would take to cure a headache or minor muscle pain. The cancer-aspirin treatment could also be viewed negatively because the lowering of cancer deaths (664 to 562) does not take into account people who suffer from hemophilia, the statistic isn't realistic when it comes to the whole world population. The fact that infants below 2 years of age who cant take aspirin because of potential Reye's syndrome is irrelevant because cancer occurs mostly at old age and even if a 1 year old developed cancer, aspirin wouldn't help because the baby wouldn't have lived for a long enough time for the aspirin to become an effective preventative measure.

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  3. The US Preventive Services Task Force has made great strides in helping subjects prevent cancer: their recent studies show that aspirin can reduce any risk of colorectal cancer and polyps. Despite these positive prevention mechanisms associated with aspirin, the aspirin regimen can actually increase the likelihood for gastrointestinal hemorrhage, which increases bleeding and, therefore, decreases clotting in the bloodstream. According to the vice president emeritus of epidemiology and surveillance research for the American Cancer Society Michael Thun, "daily aspirin at doses of 75 mg and above might lower both overall cancer incidence and overall cancer mortality." In addition, researchers also discovered a 20-30% decrease in cancer incidence in patients: the amount of cancer deaths among aspirin users reduced from 664 to 562 deaths. The recommended process for aspirin dosage is at 75-160mg to be successful at reducing risk of cancer: the mechanism of how the aspirin regime works, however, is still a concept not entirely understood by scientists.

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  4. While the cure for cancer has been a topic researched for years, it has been shown that aspirin can reduce risk of colorectal cancer and colorectal polyps by researchers including ones from the US Preventive Services Task Force. For instance, Vice president emirutus of epidemiology and surveillance research for the American Cancer Society, Michael Thun, claims that daily aspirin at doses of 75 mg and above might lower overall incidence and overall cancer mortality. On the other hand, controversy exists over the effectiveness of aspirin with studies that show that aspirin can increase risk of gastrointestinal hemorrhage, increase bleeding, and is possibly linked to Reye's syndrome. However, progress has still been seen with the use of aspirin, as shown in a recent study conducted by Dr. Peter M. Rothwell, where a 20% to 30% decrease in cancer incidence was found in patients under the aspirin regimen, and cancer deaths decreased from 664 deaths to 562 deaths. Overall, the use of aspirin seems to be a progressing success, and hopefully will one day prove to be a significant contribution to the cure for cancer.

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  5. This is breathtaking material Ms. R, I am beyond intrigued. Let's go out to lunch sometime and discuss this?

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  6. Wow! Incredible! Way to go Rau

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